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Cholic acid 3-O-glucuronide disodium

Catalog No.: A74883
FXR Agonist
Cholic acid 3-O-glucuronide disodium is an agonist of the farnesoid X receptor (FXR), exhibiting an EC50 value of 91.5 μM. This compound plays a significant role in the study of bile acid metabolism and detoxification processes. It is a valuable reagent for research applications focused on liver function and metabolic regulation.
Cholic acid 3-O-glucuronide disodium 59274-69-0 FXR Agonist
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1mg
$260.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCholic acid 3-O-glucuronide disodium is an agonist of the farnesoid X receptor (FXR), exhibiting an EC50 value of 91.5 μM. This compound plays a significant role in the study of bile acid metabolism and detoxification processes. It is a valuable reagent for research applications focused on liver function and metabolic regulation.
Product Information
Catalog NumA74883
FormulaC30H46Na2O11
Molecular Weight628.66
CAS Number59274-69-0
SMILESO[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(O[Na])=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O[Na])=O)([H])C1)C)O)C
SynonymsOCA-3-glucuronide disodium
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Metabolism > FXR