Cibenzoline is a KATP channel inhibitor targeting the pore-forming subunit Kir6.2, exhibiting an IC50 of 22.2 μM. This compound also inhibits cardiac ion currents IKr and IKs, with IC50 values of 8.8 μM and 12.3 μM, respectively. Cibenzoline is primarily utilized in the investigation of cardiac diseases, and it has been shown to induce hypoglycemia, making it relevant for studies related to glucose metabolism and endocrine functions.
Cibenzoline is a KATP channel inhibitor targeting the pore-forming subunit Kir6.2, exhibiting an IC50 of 22.2 μM. This compound also inhibits cardiac ion currents IKr and IKs, with IC50 values of 8.8 μM and 12.3 μM, respectively. Cibenzoline is primarily utilized in the investigation of cardiac diseases, and it has been shown to induce hypoglycemia, making it relevant for studies related to glucose metabolism and endocrine functions.
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