Cilastatin sodium

Catalog No.: A10886

dipeptidase inhibitor

Cilastatin sodium

Cilastatin sodium Chemical Structure

CAS NO. 81129-83-1

Cilastatin is a dipeptidase inhibitor that specifically inhibits DPEP1 (dehydrodipeptidase I), a renal membrane-bound glycoprotein involved in the hydrolytic metabolism of penem and carbapenem ??-lactam antibiotics.

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10 mg
$60.00
50 mg
$180.00
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Biological Activity

Cilastatin is a dipeptidase inhibitor that specifically inhibits DPEP1 (dehydrodipeptidase I), a renal membrane-bound glycoprotein involved in the hydrolytic metabolism of penem and carbapenem ??-lactam antibiotics.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.29 mL 131.43 mL 262.86 mL
0.5 mM 5.26 mL 26.29 mL 52.57 mL
1 mM 2.63 mL 13.14 mL 26.29 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10886
Actions Inhibitor
CAS No. 81129-83-1
Formula C16H25N2NaO5S
M. Wt 380.43
Purity >98%
Synonyms Cilastatin Monosodium Salt
SMILES O=C([[email protected]@H]1C(C)(C)C1)N/C(C([O-])=O)=C\CCCCSC[[email protected]@H](C(O)=O)N.[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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