Biological Activity
Cilastatin is a dipeptidase inhibitor that specifically inhibits DPEP1 (dehydrodipeptidase I), a renal membrane-bound glycoprotein involved in the hydrolytic metabolism of penem and carbapenem ??-lactam antibiotics.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.29 mL | 131.43 mL | 262.86 mL |
0.5 mM | 5.26 mL | 26.29 mL | 52.57 mL |
1 mM | 2.63 mL | 13.14 mL | 26.29 mL |
5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
*The above data is based on the productmolecular weight 380.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10886 |
---|---|
Actions | Inhibitor |
CAS No. | 81129-83-1 |
Formula | C16H25N2NaO5S |
M. Wt | 380.43 |
Purity | >98% |
Synonyms | Cilastatin Monosodium Salt |
SMILES | O=C([[email protected]@H]1C(C)(C)C1)N/C(C([O-])=O)=C\CCCCSC[[email protected]@H](C(O)=O)N.[Na+] |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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