Cinchocaine

Catalog No.: A17672

SChE inhibitor

Dibucaine (USAN) is an amide local anesthetic. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.
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Size Price Stock Qty
500mg
$40.00
In stock
5g
$95.00
In stock
10g
$175.00
In stock
10mM * 1mL in DMSO
$45.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Dibucaine (USAN) is an amide local anesthetic. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane. Inhibition of sodium channels prevents the depolarization of nerve cell membranes and inhibits subsequent propagation of impulses along the course of the nerve, thereby limiting the excitation of nerve endings. This results in loss of sensation.
Cell Research
Cell Line Type Value Description References
Product Information
Catalog Num A17672
Formula C20H29N3O2
Molecular Weight 343.46
CAS Number 85-79-0
SMILES CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC
Synonyms Dibucaine; Cinchocaine; Nupercainal; Nupercaine; Sovcaine; Dibucaine Base
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 59 mg/mL (171.78 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.12 mL 145.58 mL 291.15 mL
0.5 mM 5.82 mL 29.12 mL 58.23 mL
1 mM 2.91 mL 14.56 mL 29.12 mL
5 mM 0.58 mL 2.91 mL 5.82 mL
Useful Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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