CK-3197

Catalog No.: A42153
CAMP PDEl Inhibitor
CK-3197 is a selective inhibitor of cyclic 3',5'-adenosine monophosphate phosphodiesterase (cAMP PDE1), targeting enzyme activity to modulate intracellular signaling. This compound demonstrates hemodynamic and myocardial energetic effects in vivo, potentially offering therapeutic benefits in managing congestive heart failure. As an imidazolone derivative, CK-3197 serves as a positive inotropic agent, making it valuable for research related to cardiovascular function and heart disease studies.
Grouped product items
Size Price Stock Qty
25mg
$1,655.00
In stock
50mg
$2,115.00
In stock
100mg
$2,720.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCK-3197 is a selective inhibitor of cyclic 3',5'-adenosine monophosphate phosphodiesterase (cAMP PDE1), targeting enzyme activity to modulate intracellular signaling. This compound demonstrates hemodynamic and myocardial energetic effects in vivo, potentially offering therapeutic benefits in managing congestive heart failure. As an imidazolone derivative, CK-3197 serves as a positive inotropic agent, making it valuable for research related to cardiovascular function and heart disease studies.
Product Information
Catalog NumA42153
FormulaC23H22N4O3
Molecular Weight402.45
CAS Number132523-92-3
SMILESO=C(C1=C(CC)NC(N1C(C2=CC=CC=C2)=O)=O)C3=CC=C(N4C(C)=NCC4)C=C3
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