CK1δ-IN-9 is a potent inhibitor of casein kinase 1 delta (CK1δ) with an IC50 value of 1.4 nM. This compound also demonstrates inhibitory effects on p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 has favorable pharmacokinetic properties, including 70% oral bioavailability and moderate clearance, making it suitable for research applications in kinase signaling pathways and therapeutic potential in related diseases.
CK1δ-IN-9 is a potent inhibitor of casein kinase 1 delta (CK1δ) with an IC50 value of 1.4 nM. This compound also demonstrates inhibitory effects on p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 has favorable pharmacokinetic properties, including 70% oral bioavailability and moderate clearance, making it suitable for research applications in kinase signaling pathways and therapeutic potential in related diseases.
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