CL-387785 (EKI-785)

Catalog No.: A13146
EGFR inhibitor
CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.
Grouped product items
Product Name Price Stock Qty
CL-387785 10mg
$120.00
In stock
CL-387785 25mg
$250.00
In stock
CL-387785 50mg
$450.00
In stock
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Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.
Targets
Target Value
Product Information
Catalog Num A13146
Formula C18H13BrN4O
Molecular Weight 381.23
CAS Number 194423-06-8
SMILES CC#C/C(O)=N/C1=CC(C(NC2=CC=CC(Br)=C2)=NC=N3)=C3C=C1
Synonyms WAY-EKI 785, CL387785, CL 387785, EKI785, WAY-EKI785, EKI 785, EKI-785
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 61 mg/mL (160 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.23 mL 131.15 mL 262.31 mL
0.5 mM 5.25 mL 26.23 mL 52.46 mL
1 mM 2.62 mL 13.12 mL 26.23 mL
5 mM 0.52 mL 2.62 mL 5.25 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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