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Cl-4AS-1

Catalog No.: A84939
Androgen Receptor agonist
Cl-4AS-1 is a potent steroidal androgen receptor (AR) agonist with an IC50 of 12 nM. Additionally, it serves as an inhibitor of 5α-reductase types I and II, exhibiting IC50 values of 6 nM and 10 nM, respectively. This compound is valuable for studying androgen signaling pathways and investigating potential therapeutic applications in conditions related to androgen receptor modulation and steroid metabolism.
Cl-4AS-1 188589-66-4 Androgen Receptor agonist
Grouped product items
Size Price Stock Qty
1mg
$145.00
In stock
5mg
$295.00
In stock
10mg
$420.00
In stock
25mg
$750.00
In stock
50mg
$1,025.00
In stock
100mg
$1,480.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCl-4AS-1 is a potent steroidal androgen receptor (AR) agonist with an IC50 of 12 nM. Additionally, it serves as an inhibitor of 5α-reductase types I and II, exhibiting IC50 values of 6 nM and 10 nM, respectively. This compound is valuable for studying androgen signaling pathways and investigating potential therapeutic applications in conditions related to androgen receptor modulation and steroid metabolism.
Product Information
Catalog NumA84939
FormulaC26H33ClN2O2
Molecular Weight441.01
CAS Number188589-66-4
SMILESO=C([C@H]1CC[C@]2([H])[C@]1(C)CC[C@]3([H])[C@@]4(C)C=CC(N(C)[C@]4([H])CC[C@]32[H])=O)NC5=CC=CC=C5Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Endocrinology-Hormones > Androgen Receptors