Cl-amidine hydrochloride

Catalog No.: A21825

PAD inhibitor

Cl-amidine hydrochloride

Cl-amidine hydrochloride Chemical Structure

CAS NO. 1373232-26-8

Cl-amidine (hydrochloride) is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9 μM for PAD4.

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Biological Activity

Cl-amidine (hydrochloride) is a peptidylarginine deminase (PAD) inhibitor, with an IC50 5.9 μM for PAD4.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.8 mL 143.99 mL 287.99 mL
0.5 mM 5.76 mL 28.8 mL 57.6 mL
1 mM 2.88 mL 14.4 mL 28.8 mL
5 mM 0.58 mL 2.88 mL 5.76 mL

*The above data is based on the productmolecular weight 347.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21825
Actions Inhibitor
CAS No. 1373232-26-8
Formula C14H20Cl2N4O2
M. Wt 347.24
Solubility DMSO
Purity >98%
SMILES O=C(N[[email protected]](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1.[H]Cl

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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