Cladribine

Catalog No.: A10223
Cladribine is a synthetic anti-cancer agent that mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cell's ability to process DNA.
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Product Name Price Stock Qty
Cladribine 25mg
Special Price $36.00 Regular Price $45.00
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Cladribine 50mg
Special Price $56.00 Regular Price $70.00
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Cladribine 100mg
Special Price $96.00 Regular Price $120.00
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Cladribine 200mg
Special Price $160.00 Regular Price $200.00
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Cladribine 10mM * 1mL in DMSO
Special Price $51.20 Regular Price $64.00
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Important Notice: For research use only. We do not sell to patients.

Prop65 Warning  WARNING: Attention California Residents: This product can expose you to chemicals including Cladribine , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

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Biological Activity
Discription Cladribine is a synthetic anti-cancer agent that mimics the nucleoside adenosine and thus inhibits the enzyme adenosine deaminase, which interferes with the cell's ability to process DNA.
Targets
Target Value
Product Information
Catalog Num A10223
Formula C10H12ClN5O3
Molecular Weight 285.7
CAS Number 4291-63-8
SMILES C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(N=C3N)Cl)CO)O
Synonyms 2-chlorodeoxyadenosine, Leustatin
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 52 mg/mL (182.01 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+30% PEG 300+1% Tween 80+H2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35 mL 175.01 mL 350.02 mL
0.5 mM 7 mL 35 mL 70 mL
1 mM 3.5 mL 17.5 mL 35 mL
5 mM 0.7 mL 3.5 mL 7 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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