Clemastine fumarate

Catalog No.: A10226

Histamine Receptor antagonis

Clemastine fumarate

Clemastine fumarate Chemical Structure

CAS NO. 14976-57-9

Clemastine is a selective histamine H1 antagonist. It binds to the histamine H1 receptor, thus blocking the action of endogenous histamine, which leads to temporary relief of the negative symptoms caused by histamine.

Availability: In stock

Package Price Qty
100 mg

Regular Price: $60.00

Special Price $48.00

250 mg

Regular Price: $100.00

Special Price $80.00

10mM * 1mL in DMSO

Regular Price: $62.00

Special Price $49.60

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Biological Activity

Clemastine is a selective histamine H1 antagonist. It binds to the histamine H1 receptor, thus blocking the action of endogenous histamine, which leads to temporary relief of the negative symptoms caused by histamine.
Targets
Histamine H1 receptor
3 nM
In vitro DMSO Warmed: 31 mg/mL (67.39 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.74 mL 108.71 mL 217.41 mL
0.5 mM 4.35 mL 21.74 mL 43.48 mL
1 mM 2.17 mL 10.87 mL 21.74 mL
5 mM 0.43 mL 2.17 mL 4.35 mL

*The above data is based on the productmolecular weight 459.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10226
CAS No. 14976-57-9
Formula C21H26ClNO.C4H4O4
M. Wt 459.96
Purity >98%
Synonyms meclastin
SMILES C[[email protected]@](C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)OCC[[email protected]]3CCCN3C.C(=C/C(=O)O)\C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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