Clomipramine HCl

Catalog No.: A10231

5-HT Receptor agonist

Clomipramine HCl

Clomipramine HCl Chemical Structure

CAS NO. 17321-77-6

Clomipramine is a blocker of the following transporters:Serotonin transporter (SERT) (Ki = 0.14 nM),Norepinephrine transporter (NET) (Ki = 54 nM),Dopamine transporter (DAT) (Ki = 3,020 nM),Glycine transporter (GlyT/LeuT).

Availability: In stock

Package Price Qty
1000 mg
$50.00
2000 mg
$90.00
10mM * 1mL in DMSO
$59.00
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Biological Activity

Clomipramine is a blocker of the following transporters:Serotonin transporter (SERT) (Ki = 0.14 nM),Norepinephrine transporter (NET) (Ki = 54 nM),Dopamine transporter (DAT) (Ki = 3,020 nM),Glycine transporter (GlyT/LeuT).
Targets
5-HT
In vitro DMSO 60 mg/mL (170.79 mM)
Water 60 mg/mL (170.79 mM)
Ethanol 60 mg/mL (170.79 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.46 mL 142.32 mL 284.65 mL
0.5 mM 5.69 mL 28.46 mL 56.93 mL
1 mM 2.85 mL 14.23 mL 28.46 mL
5 mM 0.57 mL 2.85 mL 5.69 mL

*The above data is based on the productmolecular weight 351.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10231
Actions Agonist
CAS No. 17321-77-6
Formula C19H23ClN2.HCl
M. Wt 351.31
Solubility DMSO
Purity >98%
SMILES CN(C)CCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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