CMP3a

Catalog No.: A18347

NEK2 kinase inhibitor

CMP3a

CMP3a Chemical Structure

CAS NO. 2225902-88-3

CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$550.00
50 mg
$1,850.00
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Biological Activity

CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.59 mL 87.93 mL 175.86 mL
0.5 mM 3.52 mL 17.59 mL 35.17 mL
1 mM 1.76 mL 8.79 mL 17.59 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.6192. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18347
Actions Inhibitor
M. Wt 568.6192
Formula C28H27F3N6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2225902-88-3
Synonyms CMP 3a, CMP-3a
SMILES O=C(C1=C(O[[email protected]@H](C2=CC=CC=C2C(F)(F)F)C)C=C(C3=CN=C4C=C(C5=CN(CCN(C)C)N=C5)C=CN43)S1)N

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