CN009543V

Catalog No.: A28917
EGFR Agonist
CN009543V is an agonist of the epidermal growth factor receptor (EGFR) that promotes tyrosine phosphorylation at residues Tyr1068 and Tyr1173, leading to the activation of the MAPK/ERK signaling cascade. Additionally, CN009543V inhibits protein tyrosine phosphatase 1B (PTP-1B) activity in MDA MB468 cancer cells. This compound is applicable in cancer research, particularly in studies focusing on EGFR signaling pathways and their implications in tumor biology.
Grouped product items
Size Price Stock Qty
5mg
$180.00
In stock
10mg
$300.00
In stock
25mg
$600.00
In stock
50mg
$910.00
In stock
100mg
$1,335.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCN009543V is an agonist of the epidermal growth factor receptor (EGFR) that promotes tyrosine phosphorylation at residues Tyr1068 and Tyr1173, leading to the activation of the MAPK/ERK signaling cascade. Additionally, CN009543V inhibits protein tyrosine phosphatase 1B (PTP-1B) activity in MDA MB468 cancer cells. This compound is applicable in cancer research, particularly in studies focusing on EGFR signaling pathways and their implications in tumor biology.
Product Information
Catalog NumA28917
FormulaC12H12N4O6S
Molecular Weight340.31
CAS Number375826-84-9
SMILESO=C(OC)C(CSC1=CC=C([N+]([O-])=O)C2=NON=C21)NC(C)=O
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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