Colestolone is a 15-ketosterol compound that functions as an inhibitor of both HMG-CoA reductase and cholesteryl ester transfer protein (CETP), with an in vitro IC50 value of 660 μM. This compound exhibits cholesterol-lowering properties and is valuable in researching endocrine and metabolic diseases, particularly hyperlipidemia. Its dual action on lipid metabolism makes Colestolone a significant tool for studying cholesterol regulation and associated disorders.
Colestolone is a 15-ketosterol compound that functions as an inhibitor of both HMG-CoA reductase and cholesteryl ester transfer protein (CETP), with an in vitro IC50 value of 660 μM. This compound exhibits cholesterol-lowering properties and is valuable in researching endocrine and metabolic diseases, particularly hyperlipidemia. Its dual action on lipid metabolism makes Colestolone a significant tool for studying cholesterol regulation and associated disorders.
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