Corydamine

Catalog No.: A57205
DNA Topoisomerase I/II Inhibitor
Corydamine is a 3-arylisoquinoline alkaloid that serves as a potent inhibitor of DNA topoisomerase I and II. This compound exhibits significant anti-cancer activity and is utilized in research applications aimed at understanding the mechanisms of tumorigenesis and the development of targeted cancer therapies. Its ability to interfere with DNA manipulation makes it an important tool in the study of cellular processes and treatment modalities in oncology.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCorydamine is a 3-arylisoquinoline alkaloid that serves as a potent inhibitor of DNA topoisomerase I and II. This compound exhibits significant anti-cancer activity and is utilized in research applications aimed at understanding the mechanisms of tumorigenesis and the development of targeted cancer therapies. Its ability to interfere with DNA manipulation makes it an important tool in the study of cellular processes and treatment modalities in oncology.
Product Information
Catalog NumA57205
FormulaC20H18N2O4
Molecular Weight350.37
CAS Number49870-84-0
SMILESCNCCC1=C(C2=CC3=C(C=N2)C(OCO4)=C4C=C3)C=C(OCO5)C5=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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