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CP-724714

Catalog No.: A10242
HER2/ErbB2 inhibitor
Adooq's CP-724714 has been cited by 2 publications
CP-724714 is an orally available, small molecule, potent HER-2 tyrosine kinase inhibitor that inhibits HER2 kinase (IC50 3.8 ng/ml) .
CP-724714
Grouped product items
Product Name Price Stock Qty
CP-724714 5mg
$60.00
In stock
CP-724714 10mg
$100.00
In stock
CP-724714 25mg
$230.00
In stock
CP-724714 50mg
$400.00
In stock
CP-724714 10mM * 1mL in DMSO
$115.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's CP-724714 has been cited by 2 publications
  • Yu Muta, .et al. , Nat Commun, 2018, 9: 2174 PMID: 29872037
  • Gina M. Sizemore, .et al. , Nat Commun, 2018, 9: 2783 PMID: 30018330
    • Biological Activity
    Discription CP-724714 is an orally available, small molecule, potent HER-2 tyrosine kinase inhibitor that inhibits HER2 kinase (IC50 3.8 ng/ml) .
    Targets
    Target Value
    Product Information
    Catalog Num A10242
    Formula C27H27N5O3
    Molecular Weight 469.5
    CAS Number 537705-08-1, 383432-38-0
    SMILES CC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C=CCNC(=O)COC)C
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 83 mg/mL (176.77 mM)
    Water Insoluble
    Ethanol 83 mg/mL (176.77 mM)
    In vivo 0.5% methylcellulose 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.3 mL 106.5 mL 212.99 mL
    0.5 mM 4.26 mL 21.3 mL 42.6 mL
    1 mM 2.13 mL 10.65 mL 21.3 mL
    5 mM 0.43 mL 2.13 mL 4.26 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Protein Tyrosine Kinases > EGFR/HER2
    Angiogenesis > EGFR/HER2
    JAK/Stat > EGFR/HER2
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