Lirametostat (CPI-1205)

Catalog No.: A16357
EZH2 inhibitor

Lirametostat (CPI-1205) is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2.

Grouped product items
Product Name Price Stock Qty
Lirametostat (CPI-1205) 2mg
Special Price $72.00 Regular Price $90.00
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Lirametostat (CPI-1205) 5mg
Special Price $144.00 Regular Price $180.00
In stock
Lirametostat (CPI-1205) 10mg
Special Price $256.00 Regular Price $320.00
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Biological Activity
Discription

Lirametostat (CPI-1205) is a highly potent (biochemical IC50 = 0.002 μM, cellular EC50 = 0.032 μM) and selective inhibitor of EZH2.

Product Information
Catalog Num A16357
Formula C27H33F3N4O3
Molecular Weight 518.57
CAS Number 1621862-70-1
SMILES CC1=CC(OC)=C(CNC(C2=C(C)N([C@H](C)C3CCN(CC(F)(F)F)CC3)C4=C2C=CC=C4)=O)C(N1)=O
Synonyms CPI 1205, CPI1205
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 90 mg/mL (173.55 mM)
Water Insoluble
Ethanol 90 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.28 mL 96.42 mL 192.84 mL
0.5 mM 3.86 mL 19.28 mL 38.57 mL
1 mM 1.93 mL 9.64 mL 19.28 mL
5 mM 0.39 mL 1.93 mL 3.86 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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