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Publications citing Adooq Products
CPI-203 Citations (1)
- Derenzini E, .et al. BET Inhibition-Induced GSK3β Feedback Enhances Lymphoma Vulnerability to PI3K Inhibitors, Cell Rep, 2018, Aug 21;24(8):2155-2166 PMID: 30134175
Chemical Information
| Catalog Num | A13068 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 399.9 |
| Formula | C19H18ClN5OS |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1446144-04-2 |
| Synonyms | 0 |
| SMILES | CC1=C(SC2=C1C(=N[[email protected]](C3=NN=C(N32)C)CC(=O)N)C4=CC=C(C=C4)Cl)C |
Description |
CPI203 is a novel potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 with an IC50 of ~37 nM (BRD4 α-screen assay). | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.01 mL | 125.03 mL | 250.06mL |
| 0.5 mM | 5 mL | 25.01 mL | 50.01 mL |
| 1 mM | 2.5 mL | 12.5 mL | 25.01 mL |
| 5 mM | 0.5 mL | 2.5 mL | 5 mL |
*The above data is based on the productmolecular weight 399.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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