CPI-268456

Catalog No.: A15828
CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 (IC50 = <0.5 μM in a cell-free assay) and inhibits LPS-induced IL-6 secretion in THP-1 cells (IC50 = <0.5 μM).
Grouped product items
Product Name Price Stock Qty
CPI-268456 5mg
$140.00
In stock
CPI-268456 10mg
$250.00
In stock
CPI-268456 25mg
$550.00
In stock
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Biological Activity
Discription CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 (IC50 = <0.5 μM in a cell-free assay) and inhibits LPS-induced IL-6 secretion in THP-1 cells (IC50 = <0.5 μM).
Product Information
Catalog Num A15828
Formula C20H15Cl2N3O2
Molecular Weight 399.05
CAS Number 1380087-86-4
SMILES C(N)(=O)C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C2=CC(Cl)=CC=C2C2C(C)=NOC=21
Synonyms CPI 268456, CPI268456
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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