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CPN-351

Catalog No.: A62158
NMUR1 Antagonist
CPN-351 is a selective antagonist of the human neuropeptide FF receptor 1 (NMUR1), exhibiting a pA2 of 7.35. Its antagonistic potency towards NMUR1 is significantly greater than its effect on NMUR2, being approximately ten times more effective. CPN-351 is a valuable tool for investigating inflammatory processes and the role of neuropeptide signaling in various biological systems.
CPN-351 3057171-63-5 NMUR1 Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCPN-351 is a selective antagonist of the human neuropeptide FF receptor 1 (NMUR1), exhibiting a pA2 of 7.35. Its antagonistic potency towards NMUR1 is significantly greater than its effect on NMUR2, being approximately ten times more effective. CPN-351 is a valuable tool for investigating inflammatory processes and the role of neuropeptide signaling in various biological systems.
Product Information
Catalog NumA62158
FormulaC45H61N13O6S
Molecular Weight912.11
CAS Number3057171-63-5
SMILESC([C@@H](C(N[C@@](CC1=CC=CC=C1)(C(N[C@H](C(=O)N2[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCC2)CCCNC(=N)N)=O)C)=O)N(C(CC3=CC=CS3)=O)C)C=4C=5C(NC4)=CC=CC5
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Neuromedin U Receptor (NMUR)
GPCR/G Protein > Neuropeptide FF Receptor