Crenolanib (CP-868596)

Catalog No.: A11052
PDGFR/FLT3 Inhibitor
Crenolanib (CP-868596) is an orally bioavailable, selective small molecule inhibitor of the PDGFR tyrosine kinase, inhibiting both PDGFRA and PDGFRB at picomolar concentrations.
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Product Name Price Stock Qty
Crenolanib 5mg
Special Price $72.00 Regular Price $90.00
In stock
Crenolanib 10mg
Special Price $120.00 Regular Price $150.00
In stock
Crenolanib 50mg
Special Price $320.00 Regular Price $400.00
In stock
Crenolanib 100mg
Special Price $512.00 Regular Price $640.00
In stock
Crenolanib (CP-868596) 10mM * 1mL in DMSO
Special Price $96.00 Regular Price $120.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Crenolanib (CP-868596) has been cited by 1 publications
  • N Naganna, .et al. , EBioMedicine, 2019, Jan 24. pii: S2352-3964(19)30012-X PMID: 30686755
  • Biological Activity
    Discription Crenolanib (CP-868596) is an orally bioavailable, selective small molecule inhibitor of the PDGFR tyrosine kinase, inhibiting both PDGFRA and PDGFRB at picomolar concentrations.
    Targets
    Target Value
    Product Information
    Catalog Num A11052
    Formula C26H29N5O2
    Molecular Weight 443.5
    CAS Number 670220-88-9
    SMILES CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4
    Synonyms CP868596, CP 868596
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 84 mg/mL (189.38 mM)
    Water Insoluble
    Ethanol 7 mg/mL (15.78 mM)
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 22.55 mL 112.74 mL 225.48 mL
    0.5 mM 4.51 mL 22.55 mL 45.1 mL
    1 mM 2.25 mL 11.27 mL 22.55 mL
    5 mM 0.45 mL 2.25 mL 4.51 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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