CSD-CH2(1,8)-NH2 is a selective and competitive antagonist of the kappa opioid receptor (KOR), exhibiting a binding affinity with a Ki value of 6.8 nM. This compound effectively inhibits calcium mobilization in dorsal root ganglion (DRG) neurons and counteracts the antinociceptive effects of U50,488. CSD-CH2(1,8)-NH2 is valuable for research focused on neuropsychiatric disorders and pain modulation.
CSD-CH2(1,8)-NH2 is a selective and competitive antagonist of the kappa opioid receptor (KOR), exhibiting a binding affinity with a Ki value of 6.8 nM. This compound effectively inhibits calcium mobilization in dorsal root ganglion (DRG) neurons and counteracts the antinociceptive effects of U50,488. CSD-CH2(1,8)-NH2 is valuable for research focused on neuropsychiatric disorders and pain modulation.
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