CUDC-305 (DEBIO-0932 )

Catalog No.: A12648

HSP90 inhibitor

CUDC-305 (DEBIO-0932 ) Chemical Structure

CAS NO. 1061318-81-7

Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents.

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$170.00
25 mg
$350.00
50 mg
$550.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.59 mL 112.97 mL 225.95 mL
0.5 mM 4.52 mL 22.59 mL 45.19 mL
1 mM 2.26 mL 11.3 mL 22.59 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12648
Actions Inhibitor
M. Wt 442.58
Formula C22H30N6O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1061318-81-7
Synonyms Debio0932; CUDC305
SMILES CC(C)(C)CNCCN1C2=C(C(=NC=C2)N)N=C1SC3=CC4=C(C=C3N(C)C)OCO4

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