Cyclo (-RGDfK)

Catalog No.: A14923

αvβ3 integrin inhibitor

Cyclo (-RGDfK)

Cyclo (-RGDfK) Chemical Structure

CAS NO. 161552-03-0

Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.

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  • Julian Tu, .et al. A Stable Precursor for Bioorthogonally Removable 3-Isocyanopropyloxycarbonyl (ICPrc) Protecting Groups, Synlett, 2020, 31, A-F

Biological Activity

Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.56 mL 82.82 mL 165.65 mL
0.5 mM 3.31 mL 16.56 mL 33.13 mL
1 mM 1.66 mL 8.28 mL 16.56 mL
5 mM 0.33 mL 1.66 mL 3.31 mL

*The above data is based on the productmolecular weight 603.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14923
Actions Inhibitor
CAS No. 161552-03-0
Formula C27H41N9O7
M. Wt 603.7
Purity >98%
Synonyms Cyclic RGDFK peptide
SMILES C1C(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N[[email protected]](C(=O)N[[email protected]](C(=O)N1)CCCN=C(N)N)CCCCN)CC2=CC=CC=C2)CC(=O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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