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CyPep-1

Catalog No.: A86279
Lytic Peptide
CyPep-1 is a cationic lytic peptide that exhibits significant antitumor activity. Its mechanism involves interaction with the negatively charged membranes of cancer cells, resulting in strong cytotoxic effects. CyPep-1 demonstrates potent cytolytic activity both in vivo and in vitro, making it a valuable tool for research applications focused on solid tumors.
CyPep-1 1319804-91-5 Lytic Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCyPep-1 is a cationic lytic peptide that exhibits significant antitumor activity. Its mechanism involves interaction with the negatively charged membranes of cancer cells, resulting in strong cytotoxic effects. CyPep-1 demonstrates potent cytolytic activity both in vivo and in vitro, making it a valuable tool for research applications focused on solid tumors.
Product Information
Catalog NumA86279
FormulaC152H265N57O35
Molecular Weight3451.09
CAS Number1319804-91-5
SequenceTyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Lys-Thr-Leu-Arg-Val-Ala-Lys-Ala-Ile-Tyr-Lys-Arg-Tyr-Ile-Glu
Sequence shorteningYGRKKRRQRRRGKTLRVAKAIYKRYIE
SMILES[C@@H](CC1=CC=C(O)C=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC3=CC=C(O)C=C3)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)[C@@H](C)O)=O)CC(C)C)=O)CCCNC(=N)N)=O)[C@@H](C)C)=O)C)=O)CCCCN)=O)C)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)[C@H](CC)C)=O
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