D-KLVFFA

Catalog No.: A78250
Amyloid-β Inhibitor
D-KLVFFA is a potent inhibitor of Amyloid-β assembly, exhibiting an IC50 value of 2.6 μM. This peptide is utilized in research focused on Alzheimer's disease, providing insights into the mechanisms of amyloid plaque formation and potential therapeutic interventions. Its application can contribute to the understanding of neurodegenerative processes and the development of Alzheimer’s disease treatments.
Grouped product items
Size Price Stock Qty
1mg
$55.00
In stock
5mg
$140.00
In stock
10mg
$225.00
In stock
25mg
$365.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionD-KLVFFA is a potent inhibitor of Amyloid-β assembly, exhibiting an IC50 value of 2.6 μM. This peptide is utilized in research focused on Alzheimer's disease, providing insights into the mechanisms of amyloid plaque formation and potential therapeutic interventions. Its application can contribute to the understanding of neurodegenerative processes and the development of Alzheimer’s disease treatments.
Product Information
Catalog NumA78250
FormulaC38H57N7O7
Molecular Weight723.90
CAS Number342877-55-8
SequenceD-Lys-D-Leu-D-Val-D-Phe-D-Phe-D-Ala
Sequence shorteningd-KLVFFA
SMILES[C@@H](CC1=CC=CC=C1)(C(N[C@H](CC2=CC=CC=C2)C(N[C@@H](C(O)=O)C)=O)=O)NC([C@H](NC([C@H](NC([C@@H](CCCCN)N)=O)CC(C)C)=O)C(C)C)=O
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