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D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.13 mL | 105.65 mL | 211.3 mL |
| 0.5 mM | 4.23 mL | 21.13 mL | 42.26 mL |
| 1 mM | 2.11 mL | 10.56 mL | 21.13 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.23 mL |
*The above data is based on the productmolecular weight 473.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18688 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1236767-85-3 |
| Formula | C17H11F8N3O4 |
| M. Wt | 473.27 |
| Purity | >98% |
| SMILES | O=C1C2=C(N=C(N1C3=CC=C(C=C3)OCC(F)(F)F)OCC(F)(C(F)(F)F)F)NC(C2)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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