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Darapladib

Catalog No.: A14274

Lp-PLA2 Inhibitor

Darapladib

Darapladib Chemical Structure

CAS NO. 356057-34-6

Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor .

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$180.00
25 mg
$400.00
10mM * 1mL in DMSO
$180.00
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Biological Activity

Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor .
Targets
Lp-PLA2
0.25 nM
In vitro DMSO Warmed: 96 mg/mL (143.97 mM)
Water Insoluble
Ethanol 96 mg/mL (143.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15 mL 74.99 mL 149.98 mL
0.5 mM 3 mL 15 mL 30 mL
1 mM 1.5 mL 7.5 mL 15 mL
5 mM 0.3 mL 1.5 mL 3 mL

*The above data is based on the productmolecular weight 666.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14274
Actions Inhibitor
CAS No. 356057-34-6
Formula C36H38F4N4O2S
M. Wt 666.77
Purity >98%
Synonyms SB-480848
SMILES CCN(CC)CCN(CC1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)C(=O)CN3C4=C(CCC4)C(=O)N=C3SCC5=CC=C(C=C5)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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