Darifenacin-d4

Catalog No.: A61381
Stable Isotope
Darifenacin-d4 is a deuterium-labeled derivative of Darifenacin, which acts as a selective antagonist for the M3 muscarinic receptor, exhibiting a pKi value of 8.9. This stable isotope compound is valuable for pharmacokinetic studies and metabolic research, allowing for precise tracking of the parent compound and its metabolites in biological systems. Its use in isotope labeling enhances analytical techniques such as mass spectrometry in studying receptor interactions and drug metabolism.
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5mg
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDarifenacin-d4 is a deuterium-labeled derivative of Darifenacin, which acts as a selective antagonist for the M3 muscarinic receptor, exhibiting a pKi value of 8.9. This stable isotope compound is valuable for pharmacokinetic studies and metabolic research, allowing for precise tracking of the parent compound and its metabolites in biological systems. Its use in isotope labeling enhances analytical techniques such as mass spectrometry in studying receptor interactions and drug metabolism.
Product Information
Catalog NumA61381
FormulaC28H26D4N2O2
Molecular Weight430.57
CAS Number1095598-84-7
SMILESNC(C(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H]3CN(CC3)C([2H])([2H])C([2H])([2H])C4=CC=C(OCC5)C5=C4)=O
SynonymsUK-88525-d4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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