Dauricinoline

Catalog No.: A79641
NF-κB Inhibitor
Dauricinoline is a potent orally active inhibitor of NF-κB, effectively blocking NF-κB activation induced by TNF-α. This compound demonstrates significant anti-inflammatory activity, making it a valuable tool for investigating inflammatory diseases, particularly in the context of lung inflammation. Researchers may utilize Dauricinoline to explore the mechanisms underlying NF-κB-mediated signaling pathways and their role in various inflammatory conditions.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDauricinoline is a potent orally active inhibitor of NF-κB, effectively blocking NF-κB activation induced by TNF-α. This compound demonstrates significant anti-inflammatory activity, making it a valuable tool for investigating inflammatory diseases, particularly in the context of lung inflammation. Researchers may utilize Dauricinoline to explore the mechanisms underlying NF-κB-mediated signaling pathways and their role in various inflammatory conditions.
Product Information
Catalog NumA79641
FormulaC37H42N2O6
Molecular Weight610.74
CAS Number30984-80-6
SMILESOC1=CC2=C([C@@H](CC3=CC=C(O)C(OC4=CC=C(C[C@H]5N(C)CCC6=C5C=C(OC)C(OC)=C6)C=C4)=C3)N(C)CC2)C=C1OC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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