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Davalomilast

Catalog No.: A41953
PDE4 Inhibitor
Davalomilast is a selective phosphodiesterase 4 (PDE4) inhibitor known for its anti-inflammatory properties. This compound is of particular interest in research on autoimmune diseases and dermatological conditions, where it may modulate inflammatory responses and provide therapeutic insights. Its mechanism suggests potential applications in alleviating symptoms associated with various inflammatory disorders.
Davalomilast 2379980-45-5 PDE4 Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDavalomilast is a selective phosphodiesterase 4 (PDE4) inhibitor known for its anti-inflammatory properties. This compound is of particular interest in research on autoimmune diseases and dermatological conditions, where it may modulate inflammatory responses and provide therapeutic insights. Its mechanism suggests potential applications in alleviating symptoms associated with various inflammatory disorders.
Product Information
Catalog NumA41953
FormulaC20H21F2NO3S
Molecular Weight393.45
CAS Number2379980-45-5
SMILESFC(F)OC(C=CC(/C=C/N1C(C)=CC(C=C1C)=O)=C2)=C2O[C@@H]3CCSC3
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Metabolism > PDE