DC271

Catalog No.: A45007
RAR Agonist
DC271 is a potent RAR agonist that functions as a retinoid, stimulating cellular responses similar to those of endogenous retinoic acid (ATRA) and the synthetic retinoid EC23. By binding to retinoid protein machinery such as CRABPII, DC271 facilitates the translocation of ATRA into the nucleus, enhancing retinoid signaling pathways. This compound is valuable for research applications involving gene expression regulation, differentiation, and cellular growth in various biological contexts.
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5mg
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50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDC271 is a potent RAR agonist that functions as a retinoid, stimulating cellular responses similar to those of endogenous retinoic acid (ATRA) and the synthetic retinoid EC23. By binding to retinoid protein machinery such as CRABPII, DC271 facilitates the translocation of ATRA into the nucleus, enhancing retinoid signaling pathways. This compound is valuable for research applications involving gene expression regulation, differentiation, and cellular growth in various biological contexts.
Product Information
Catalog NumA45007
FormulaC23H25NO2
Molecular Weight347.45
CAS Number198696-03-6
SMILESO=C(O)C1=CC=C(C#CC2=CC3=C(N(C(C)C)CCC3(C)C)C=C2)C=C1
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