DCM-ONOO is a near-infrared two-photon fluorescent probe targeting peroxynitrite (ONOO⁻) for real-time monitoring. This reagent features excellent optical properties, with a single photon excitation at 520 nm and emission at 685 nm, and a two-photon excitation at 820 nm. Upon interaction with ONOO⁻, DCM-ONOO exhibits a significant fluorescence shift from 460 nm to 512 nm, enabling specific detection of ONOO⁻ in biological samples. DCM-ONOO has been effectively utilized in rat models of epilepsy, offering insights into the dynamic fluctuations of peroxynitrite in neurological conditions.
DCM-ONOO is a near-infrared two-photon fluorescent probe targeting peroxynitrite (ONOO⁻) for real-time monitoring. This reagent features excellent optical properties, with a single photon excitation at 520 nm and emission at 685 nm, and a two-photon excitation at 820 nm. Upon interaction with ONOO⁻, DCM-ONOO exhibits a significant fluorescence shift from 460 nm to 512 nm, enabling specific detection of ONOO⁻ in biological samples. DCM-ONOO has been effectively utilized in rat models of epilepsy, offering insights into the dynamic fluctuations of peroxynitrite in neurological conditions.
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