Deforolimus (Ridaforolimus)

Catalog No.: A10295

mTOR Inhibitor

Deforolimus (Ridaforolimus)

Deforolimus (Ridaforolimus) Chemical Structure

CAS NO. 572924-54-0

Deforolimus (Ridaforolimus) is an investigational targeted and small-molecule inhibitor of the protein mTOR. Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.

Availability: In stock

Package Price Qty
5 mg
$55.00
10 mg
$77.00
50 mg
$296.00
100 mg
$500.00
10mM * 1mL in DMSO
$178.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Deforolimus (Ridaforolimus) is an investigational targeted and small-molecule inhibitor of the protein mTOR. Blocking mTOR creates a starvation-like effect in cancer cells by interfering with cell growth, division, metabolism, and angiogenesis.

Targets
mTOR (HT-1080 cells)
0.2 nM
In vitro (25°C) DMSO 198 mg/mL (199.95 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.1 mL 50.49 mL 100.99 mL
0.5 mM 2.02 mL 10.1 mL 20.2 mL
1 mM 1.01 mL 5.05 mL 10.1 mL
5 mM 0.2 mL 1.01 mL 2.02 mL

*The above data is based on the productmolecular weight 990.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10295
Actions Inhibitor
M. Wt 990.2
Formula C53H84NO14P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 572924-54-0
Synonyms AP23573, MK-8669, MK8669
SMILES C[[email protected]@H]1CC[[email protected]]2C[[email protected]@H](/C(=C/C=C/C=C/[[email protected]](C[[email protected]](C(=O)[[email protected]@H]([[email protected]@H](/C(=C/[[email protected]](C(=O)C[[email protected]](OC(=O)[[email protected]@H]3CCCCN3C(=O)C(=O)[[email protected]@]1(O2)O)[[email protected]](C)C[[email protected]@H]4CC[[email protected]]([[email protected]@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC

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