Biological Activity
Detomidine is a sedative with analgesic properties. α2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters.
Targets
Adrenergic Receptor | ||||
In vitro | DMSO | 45 mg/mL (202.05 mM) | |
Water | 45 mg/mL (202.05 mM) | ||
Ethanol | 45 mg/mL (202.05 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 44.9 mL | 224.52 mL | 449.03 mL |
0.5 mM | 8.98 mL | 44.9 mL | 89.81 mL |
1 mM | 4.49 mL | 22.45 mL | 44.9 mL |
5 mM | 0.9 mL | 4.49 mL | 8.98 mL |
*The above data is based on the productmolecular weight 222.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10298 |
---|---|
Actions | Agonist |
M. Wt | 222.7 |
Formula | C12H14N2.HCl |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 90038-01-0 |
SMILES | CC1=C(C(=CC=C1)CC2=CN=CN2)C.Cl |
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