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Biological Activity
Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin.
Targets
| In vitro | DMSO | Warmed: 55 mg/mL (180.48 mM) | |
| Water | Warmed: 55 mg/mL (180.48 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.82 mL | 164.1 mL | 328.19 mL |
| 0.5 mM | 6.56 mL | 32.82 mL | 65.64 mL |
| 1 mM | 3.28 mL | 16.41 mL | 32.82 mL |
| 5 mM | 0.66 mL | 3.28 mL | 6.56 mL |
*The above data is based on the productmolecular weight 304.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10300 |
|---|---|
| CAS No. | 149003-01-0 |
| Formula | C11H17ClN4O4 |
| M. Wt | 304.7 |
| Purity | >98% |
| Synonyms | Totect, ICRF-187, Zinecard, Cardioxane |
| SMILES | C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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