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Dexrazoxane HCl

Catalog No.: A10300

Dexrazoxane HCl

Dexrazoxane HCl Chemical Structure

CAS NO. 149003-01-0

Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin.

Availability: In stock

Package Price Qty
5 mg
$30.00
10 mg
$50.00
50 mg
$95.00
100 mg
$130.00
10mM * 1mL in DMSO
$55.00
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Biological Activity

Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin.
Targets
In vitro DMSO Warmed: 55 mg/mL (180.48 mM)
Water Warmed: 55 mg/mL (180.48 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.82 mL 164.1 mL 328.19 mL
0.5 mM 6.56 mL 32.82 mL 65.64 mL
1 mM 3.28 mL 16.41 mL 32.82 mL
5 mM 0.66 mL 3.28 mL 6.56 mL

*The above data is based on the productmolecular weight 304.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10300
CAS No. 149003-01-0
Formula C11H17ClN4O4
M. Wt 304.7
Purity >98%
Synonyms Totect, ICRF-187, Zinecard, Cardioxane
SMILES C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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