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DG172 dihydrochloride

PPARβ/δ inverse agonist

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Catalog No. A16309

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
DG172 dihydrochloride 5mg A16309-5
$50.00
DG172 dihydrochloride 10mg A16309-10
$90.00
DG172 dihydrochloride 50mg A16309-50
$360.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

DG-172 is an orally active potent PPARβ/δ inverse agonist (IC50 = 26.9 nM). DG-172 inhibits Angptl4 gene expression in mouse myoblasts (IC50 = 9.5 nM) in vitro.

DG172 dihydrochloride

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Chemical Information

Catalog Num A16309
Actions Antagonist
M. Wt 455.22
Formula C20H22BrCl2N3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1361504-77-9
Synonyms DG 172 dihydrochloride
SMILES N#C/C(C1=CC=CC=C1Br)=C\C2=CC=C(N3CCN(C)CC3)C=C2.[H]Cl.[H]Cl

Biological Activity

Description
DG-172 is an orally active potent PPARβ/δ inverse agonist (IC50 = 26.9 nM). DG-172 inhibits Angptl4 gene expression in mouse myoblasts (IC50 = 9.5 nM) in vitro.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.97 mL 109.84 mL 219.67mL
0.5 mM 4.39 mL 21.97 mL 43.93 mL
1 mM 2.2 mL 10.98 mL 21.97 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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