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DGN549-L

Catalog No.: A41585
DNA Alkylator
DGN549-L is a DNA alkylator that facilitates the alkylation of DNA, allowing for efficient conjugation to antibodies at lysine residues. This compound is particularly useful in the synthesis of antibody-drug conjugates (ADCs), enabling targeted delivery of therapeutic agents. Its application in bioconjugation research supports advancements in precision medicine and therapeutic development.
DGN549-L 1884276-68-9 DNA Alkylator
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Size Price Stock Qty
5mg
$4,175.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDGN549-L is a DNA alkylator that facilitates the alkylation of DNA, allowing for efficient conjugation to antibodies at lysine residues. This compound is particularly useful in the synthesis of antibody-drug conjugates (ADCs), enabling targeted delivery of therapeutic agents. Its application in bioconjugation research supports advancements in precision medicine and therapeutic development.
Product Information
Catalog NumA41585
FormulaC58H58N8O13
Molecular Weight1075.13
CAS Number1884276-68-9
SMILESO=C(C1=C2)N3C4=CC=CC=C4C[C@@]3([H])CNC1=CC(OCC5=CC(COC(C=C(N=C[C@@]6([H])N(C7=CC=CC=C7C6)C8=O)C8=C9)=C9OC)=CC(NC([C@H](C)NC([C@H](C)NC(CCCCC(ON(C%10=O)C(CC%10)=O)=O)=O)=O)=O)=C5)=C2OC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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DNA Damage > DNA alkylator