DHODH-IN-25 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 value of 5.4 nM for human DHODH. This compound demonstrates significant biological activity and is particularly relevant for research applications involving acute myeloid leukemia (AML). DHODH-IN-25 provides valuable insights into the therapeutic potential of targeting pyrimidine biosynthesis in cancer treatment.
DHODH-IN-25 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 value of 5.4 nM for human DHODH. This compound demonstrates significant biological activity and is particularly relevant for research applications involving acute myeloid leukemia (AML). DHODH-IN-25 provides valuable insights into the therapeutic potential of targeting pyrimidine biosynthesis in cancer treatment.
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