DHODH-IN-34

Catalog No.: A70051
DHODH Inhibitor
DHODH-IN-34 is a selective inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 13 nM. This compound is particularly valuable for researching RNA viruses, including measles virus and chikungunya virus, due to its ability to disrupt nucleotide synthesis pathways critical for viral replication. Researchers can leverage DHODH-IN-34 to investigate therapeutic strategies against these viral infections.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDHODH-IN-34 is a selective inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 13 nM. This compound is particularly valuable for researching RNA viruses, including measles virus and chikungunya virus, due to its ability to disrupt nucleotide synthesis pathways critical for viral replication. Researchers can leverage DHODH-IN-34 to investigate therapeutic strategies against these viral infections.
Product Information
Catalog NumA70051
FormulaC19H20F2N4O2
Molecular Weight374.38
CAS Number1644156-93-3
SMILESCCC1=CN=C(N2N=C(OC(C)C)C(OC3=C(F)C=CC=C3F)=C2C)N=C1
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