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Dimethothiazine hydrochloride

Catalog No.: A34049
Antihistamine/Anti-5-HT Agent
Dimethothiazine hydrochloride is an orally active tricyclic antihistamine and anti-5-HT agent. It exhibits notable efficacy against decerebrate rigidity, demonstrating minimal sedative and soporific effects. This compound has been shown to diminish or eliminate the influence of fusimotor activity on the muscle spindle in decerebrate cats. Dimethothiazine hydrochloride is valuable for research on hemicrania and spasticity.
Dimethothiazine hydrochloride 34396-64-0 Antihistamine/Anti-5-HT Agent
Grouped product items
Size Price Stock Qty
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
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Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDimethothiazine hydrochloride is an orally active tricyclic antihistamine and anti-5-HT agent. It exhibits notable efficacy against decerebrate rigidity, demonstrating minimal sedative and soporific effects. This compound has been shown to diminish or eliminate the influence of fusimotor activity on the muscle spindle in decerebrate cats. Dimethothiazine hydrochloride is valuable for research on hemicrania and spasticity.
Product Information
Catalog NumA34049
FormulaC19H26ClN3O2S2
Molecular Weight428.01
CAS Number34396-64-0
SMILESO=S(C1=CC=C2SC3=C(N(CC(C)N(C)C)C2=C1)C=CC=C3)(N(C)C)=O.Cl
SynonymsDimetotiazine hydrochloride; Fonazine hydrochloride
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > 5-HT Receptors
GPCR/G Protein > Histamine Receptors