DL-Gabaculine hydrochloride is an irreversible inhibitor of bacterial pyridoxal phosphate-linked γ-aminobutyric acid-α-ketoglutaric acid transaminase, with a Ki of 2.86 μM. This neurotoxin effectively disrupts GABA metabolism, leading to increased levels of γ-aminobutyric acid in biological systems. It is utilized primarily in research applications focused on neuropharmacology and the study of neurotransmitter regulation.
DL-Gabaculine hydrochloride is an irreversible inhibitor of bacterial pyridoxal phosphate-linked γ-aminobutyric acid-α-ketoglutaric acid transaminase, with a Ki of 2.86 μM. This neurotoxin effectively disrupts GABA metabolism, leading to increased levels of γ-aminobutyric acid in biological systems. It is utilized primarily in research applications focused on neuropharmacology and the study of neurotransmitter regulation.
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