Dolasetron
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Dolasetron is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. | ||
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Catalog Num | A17595 |
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Formula | C19H20N2O3 |
Molecular Weight | 324.37 |
CAS Number | 115956-12-2 |
SMILES | O=C(C1=CNC2=C1C=CC=C2)OC(CC3N4C5)C[C@@]4([H])CC(C3)C5=O |
Synonyms | HSDB 7565; HSDB7565; HSDB-7565; Dolasetron; Dolasetronum |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 61 mg/mL (188.05 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 30.83 mL | 154.14 mL | 308.29 mL |
0.5 mM | 6.17 mL | 30.83 mL | 61.66 mL |
1 mM | 3.08 mL | 15.41 mL | 30.83 mL |
5 mM | 0.62 mL | 3.08 mL | 6.17 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2