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Biological Activity
Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.47 mL | 77.37 mL | 154.75 mL |
| 0.5 mM | 3.09 mL | 15.47 mL | 30.95 mL |
| 1 mM | 1.55 mL | 7.74 mL | 15.47 mL |
| 5 mM | 0.31 mL | 1.55 mL | 3.09 mL |
*The above data is based on the productmolecular weight 646.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12552 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 2088518-50-5 |
| Formula | C32H36ClN9O2S |
| M. Wt | 646.21 |
| Purity | >98% |
| SMILES | CC1=NC=CC=C1C2=C(Cl)SC3=CC=C(NC(NCC(NCCCN(C)[[email protected]@H]4CCCN(C5=C(C=CN6)C6=NC=N5)C4)=O)=O)C=C32 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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