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Catalog No.: A12552

Dot1L inhibitor


Dot1L-IN-1 Chemical Structure

CAS NO. 2088518-50-5

Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Dot1L-IN-1 is a highly potent, selective and structurally novel Dot1L inhibitor with a Ki of 2 pM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.47 mL 77.37 mL 154.75 mL
0.5 mM 3.09 mL 15.47 mL 30.95 mL
1 mM 1.55 mL 7.74 mL 15.47 mL
5 mM 0.31 mL 1.55 mL 3.09 mL

*The above data is based on the productmolecular weight 646.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12552
Actions Inhibitor
CAS No. 2088518-50-5
Formula C32H36ClN9O2S
M. Wt 646.21
Purity >98%
SMILES CC1=NC=CC=C1C2=C(Cl)SC3=CC=C(NC(NCC(NCCCN(C)[[email protected]@H]4CCCN(C5=C(C=CN6)C6=NC=N5)C4)=O)=O)C=C32

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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