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DPPI 1c hydrochloride is a dicyanopyrrolidine compound that acts as a slow-binding and active site-targeting inhibitor of CD26 (DPP 4), with an IC50 = 106 nM and little activity against DPP II, DPP III, DPP VIII, DPP IX, FAP, or APP even at concentrations as high as 30 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.97 mL | 159.85 mL | 319.69 mL |
| 0.5 mM | 6.39 mL | 31.97 mL | 63.94 mL |
| 1 mM | 3.2 mL | 15.98 mL | 31.97 mL |
| 5 mM | 0.64 mL | 3.2 mL | 6.39 mL |
*The above data is based on the productmolecular weight 312.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15298 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 866396-34-1 |
| Formula | C14H20N4O2.HCl |
| M. Wt | 312.8 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | Dipeptidylpeptidase IV Inhibitor III |
| SMILES | C1CCC(C1)(CO)NCC(=O)N2C(CCC2C#N)C#N.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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