DPTIP is a selective inhibitor of neutral sphingomyelinase 2 (N-SMase 2), demonstrating a potent inhibitory activity with an IC50 of 30 nM. This compound effectively penetrates the blood-brain barrier, making it a valuable tool for studying the biological roles of N-SMase 2 in various neurobiological processes. Its application in research includes investigating exosome biogenesis and sphingolipid metabolism, providing insights into cellular signaling pathways in neurological disorders.
DPTIP is a selective inhibitor of neutral sphingomyelinase 2 (N-SMase 2), demonstrating a potent inhibitory activity with an IC50 of 30 nM. This compound effectively penetrates the blood-brain barrier, making it a valuable tool for studying the biological roles of N-SMase 2 in various neurobiological processes. Its application in research includes investigating exosome biogenesis and sphingolipid metabolism, providing insights into cellular signaling pathways in neurological disorders.
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