DS20362725 is an agonist of the estrogen-related receptor alpha (ERRα). It demonstrates potent inhibition of the binding between receptor-interacting protein 140 (RIP140) corepressor peptide and the GST-ERRα ligand-binding domain, with an IC50 value of 0.6 μM. This compound is valuable for research on metabolic disorders, particularly type 2 diabetes mellitus (T2DM), enabling investigations into ERRα's role in metabolic regulation.
DS20362725 is an agonist of the estrogen-related receptor alpha (ERRα). It demonstrates potent inhibition of the binding between receptor-interacting protein 140 (RIP140) corepressor peptide and the GST-ERRα ligand-binding domain, with an IC50 value of 0.6 μM. This compound is valuable for research on metabolic disorders, particularly type 2 diabetes mellitus (T2DM), enabling investigations into ERRα's role in metabolic regulation.
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