Duocarmycin analog-1

Catalog No.: A37306
DNA Alkylator/Crosslinker
Duocarmycin analog-1 is a potent DNA alkylator and crosslinker, functioning through the formation of covalent bonds with DNA, leading to cellular damage and apoptosis. It is a valuable tool in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. This compound is primarily utilized in research involving DNA interactions and cancer treatment modalities.
Grouped product items
Size Price Stock Qty
1mg
$465.00
In stock
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDuocarmycin analog-1 is a potent DNA alkylator and crosslinker, functioning through the formation of covalent bonds with DNA, leading to cellular damage and apoptosis. It is a valuable tool in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. This compound is primarily utilized in research involving DNA interactions and cancer treatment modalities.
Product Information
Catalog NumA37306
FormulaC34H31ClN4O5
Molecular Weight611.09
CAS Number372954-15-9
SMILESO=C(OC(C)(C)C)NC1=CC=C(C(NC2=CC3=C(NC(C(N4C[C@@H](CCl)C5=C4C=C(O)C6=CC=CC=C56)=O)=C3)C=C2)=O)C=C1
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2