Catalog No.
Product Name
Application
Product Information
Citations
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Esterase Fluorescent Substrate
5(6)-Carboxynaphthofluorescein diacetate is a specific fluorescent substrate utilized in esterase assays. It is cleaved by intracellular esterases, leading to the production of red fluorescence, which can be quantitatively measured to assess enzyme activity. This compound is instrumental in various biological and biochemical research applications, including monitoring esterase activity in live cells. -
Fluorescent Dye
Ac-DNLD-AMC is a fluorogenic substrate specifically designed for the detection of caspase-3 activity. Upon cleavage by this enzyme, Ac-DNLD-AMC releases the fluorescent moiety 7-amino-4-methylcoumarin (AMC), enabling sensitive quantification of caspase-3 enzymatic activity. This reagent is valuable in apoptosis research and the study of cellular processes involving programmed cell death. -
Fluorescent Dye
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye primarily utilized for its ability to measure enzymatic activity related to galactose-6-sulfate sulfatase. This compound plays a crucial role in the diagnosis of mucopolysaccharidosis IV A by providing a sensitive method for detecting enzyme activity. Its fluorescence properties enhance analysis in biochemical assays, making it valuable in research applications focused on lysosomal storage disorders. -
Fluorescent Dye
Naphthalene-1,2-dicarbaldehyde is a fluorogenic compound widely used as a fluorescent dye in biochemical research. Its unique structural properties allow for effective incorporation into various biochemical assays, enabling sensitive detection of target molecules. This reagent is particularly valuable in studies involving protein interactions and cellular imaging, facilitating enhanced visualization in fluorescence microscopy applications. -
Fluorescent Substrate
4-Methylumbelliferyl phosphate (2-amino-2-methyl-1,3-propanediol) serves as a fluorescent substrate primarily utilized in enzyme assays. This compound exhibits fluorescence upon enzymatic hydrolysis, making it an effective tool for studying enzyme activity and kinetics. Its applications extend to various biochemical assays, facilitating the detection and quantification of specific enzymatic reactions. -
Fluorescent Dye
6-Chloro-3-indoxyl-α-D-mannopyranoside serves as a chromogenic substrate specifically for α-mannosidase. Upon enzymatic cleavage, it produces a distinctive salmon-colored precipitate, allowing for easy visualization. This compound is widely used in biochemical assays to study α-mannosidase activity and facilitate the identification of mannosidase-producing microorganisms. -
Fluorescent Dye
3-Acetylumbelliferyl β-D-Glucopyranoside serves as a fluorogenic substrate specifically for β-glucosidase, facilitating the detection of enzymatic activity through fluorescence. This compound is valuable as a positive control in assays involving β-D-glucosidase, enabling researchers to evaluate enzyme function and activity in various biological systems. Its application in fluorescence-based assays enhances the understanding of β-glucosidase involvement in numerous biological processes. -
Fluorescent Dye
4-Methylumbelliferyl Decanoate is a fluorogenic substrate primarily utilized for monitoring the hydrolytic activity of carboxylesterases. When cleaved by these enzymes, it emits fluorescence, facilitating the detection and quantification of enzyme activity in biological samples. This reagent is instrumental in studies involving drug metabolism, enzyme kinetics, and the functional characterization of esterases in various biological systems. -
Fluorescent Dye
5-Bromo-1H-indol-3-yl octanoate is a fluorescent dye that serves as a chromogenic substrate for esterases, specifically exhibiting C8 activity. Upon enzymatic cleavage, this compound produces a blue precipitate, enabling visual detection and quantification of esterase activity in various biological samples. It is valuable for research applications aiming to study enzyme kinetics and cellular processes involving ester hydrolysis. -
Fluorescent Dye
N-Acetyl-DL-phenylalanine β-naphthyl ester acts as a fluorescent dye and a chromogenic substrate for chymotrypsin and microbial serine proteases, including subtilisin. This compound is valuable in biochemical research for the detection and characterization of proteolytic enzymes. Its fluorescent properties facilitate imaging and analysis in protease-related studies. -
Fluorescent Dye
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye utilized as a fluorogenic substrate for aspartyl proteinases derived from human malaria parasites. This compound exhibits enhanced fluorescence upon cleavage, making it an effective tool in studying enzyme activity and kinetics. Its applications extend to research focusing on malaria pathogenesis and the development of potential therapeutic strategies against the disease. -
Fluorescent Dye
4-Methylumbelliferyl β-cellotrioside is a fluorescent substrate specifically designed for the detection and quantification of β-glycosidase enzymes. This compound incorporates a cellulose fluorescent derivative, allowing for sensitive imaging and analysis of enzyme activity. It is widely utilized in biochemical assays to study glycoside hydrolysis and investigate cellulose degradation mechanisms in various biological systems. -
Fluorescent Dye
Glut-Phe-AMC is a fluorescent dye primarily used for monitoring proteolytic activity. This substrate is cleaved by proteases, releasing the fluorescent aminomethylcoumarin (AMC) moiety, which allows for sensitive detection in various biological assays. Its application is particularly valuable in studies involving enzyme activity, protein degradation, and cellular processes. Glut-Phe-AMC serves as an essential tool for researchers exploring protease functions in numerous biological contexts. -
Styryl Dye
RH 421 is a voltage-sensitive styryl dye that targets lipid bilayers, enabling its use in studies of membrane potential changes. As a chromogenic substrate for β-galactosidase, it serves important roles in cellular imaging and assay development. This compound is valuable in electrophysiological research and the investigation of membrane dynamics. -
Fluorescent Products
3-BTMD is a fluorescent compound generated through the action of the COMT enzyme on its substrate, 3-BTD, exhibiting an excitation wavelength of 390 nm and an emission wavelength of 510 nm. This reagent is primarily utilized in fluorescent labeling and imaging applications, facilitating the study of enzymatic activity and biomolecular interactions in various biological contexts. Its distinct fluorescence properties make it a valuable tool for researchers in the fields of biochemistry and molecular biology. -
Fluorescent Dye
2-Chloro-4-nitrophenyl-α-D-glucopyranoside serves as a chromogenic substrate targeting enzymatic activity. It is particularly useful for assays measuring the release of 2-chloro-4-nitrophenol (CNP) from conjugated carbohydrates, making it a valuable tool in the study of glycosyltransferases. This compound can aid in understanding carbohydrate metabolism and enzyme kinetics. -
Fluorescent Dye
2,6-Dibromo-4-(chloroimino)cyclohexa-2,5-dienone serves as a colorimetric dye primarily targeting phenolic compounds. At an approximate pH of 9.4, it reacts with phenolics to yield an indigo product, enabling sensitive detection. This reagent is notably employed as a Gibbs reagent for the colorimetric analysis of phenolic substances and has demonstrated utility in quantifying aflatoxins, transforming their colorless form to a green hue with an absorption peak at 673 nm. -
Fluorescent Dye
4-Nitrophenyl β-D-cellotetraoside is a fluorescent dye that functions as a cellulose mimetic, comprising a tetramer of D-glucose units with β-1-4 glycosidic bonds. It serves as a substrate for enzymatic hydrolysis, allowing researchers to analyze the fragmentation pattern via thin-layer chromatography or by quantifying the release of 4-nitrophenol, which exhibits strong absorbance at 395 nm in alkaline solutions. This reagent is particularly useful in studies of cellulose degradation, enabling the assessment of cellulase specificity and activity. -
Fluorescent Dye
4-Nitrophenyl β-D-cellotrioside is a chromogenic substrate specifically designed for endoglucanases and cellulose biohydrolases. This compound serves as a fluorescent dye, undergoing hydrolysis by enzymes to release 4-nitrophenol, which results in a distinct yellow color. The enzymatic activity can be quantitatively assessed by measuring the absorbance change at 405 nm, making it a useful tool for studying cellulose degradation and enzyme kinetics in various biological research applications. -
Dye
N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid sodium, commonly known as 1,8-EDNAS sodium, serves as a multifunctional dye primarily targeting biological research. This compound is instrumental in visualizing and analyzing cell structures, tracking biomolecules, evaluating cellular functions, and differentiating cell types. Its diverse applications extend from fundamental scientific investigations to clinical diagnostics, in addition to traditional uses in textile dyeing and emerging areas such as food pigments and dye-sensitized solar cells. -
Fluorescent Probe
CDy14 is a fluorescent probe that targets the extracellular polysaccharide Psl, facilitating the visualization and detection of biofilms. This reagent is valuable for studying chronic bacterial infections, providing insights into microbial communities and their persistence in various environments. Researchers can utilize CDy14 to enhance understanding of biofilm-associated pathogenesis and antibiotic resistance mechanisms. -
Mycobacterium tuberculosis Fluorescent Probe
CDG-DNB3 is a selective fluorescent probe targeting Mycobacterium tuberculosis. It enables rapid and specific labeling of live bacterial cultures, facilitating real-time imaging of Bacillus Calmette-Guérin phagocytosis. This probe is essential for studying the interactions between the pathogen and host cells, contributing to research in tuberculosis diagnostics and therapeutics. -
Dye
Ruthenium red is a polycationic dye primarily used for electron microscopy applications in the analysis of cells, tissues, and vegetative bacteria. It exhibits a strong interaction with phospholipids and fatty acids while binding effectively to acidic mucopolysaccharides. Additionally, Ruthenium red functions as a blocker of L-type calcium currents (ICa), making it valuable for studies involving cellular calcium dynamics. -
Photoinitiator/Fluorescent Whitening Agent
Fluorescent Brightener 28 is a fluorescent whitening agent and photoinitiator that functions primarily through emission of visible light. This compound can effectively stain polysaccharides, including cellulose, and shows utility in marking the cytoplasm and cell nucleus upon membrane rupture. Additionally, it serves as a tool for detecting intracellular chitin in living cells. Fluorescent Brightener 28 is also sensitive to LED light, making it suitable for applications in free radical photopolymerizations. -
Fluorescent Probe
NADA-green is a fluorescent D-amino acid probe designed to target peptidoglycan biosynthesis in a range of bacterial species. This reagent is efficiently incorporated into the bacterial cell wall, enabling real-time monitoring of bacterial growth with minimal disturbance to cellular processes. NADA-green is an invaluable tool for researchers studying bacterial physiology and cell wall dynamics. -
Composite Dye
Giemsa stain is a composite dye that functions primarily as a histological stain. This reagent effectively stains chromatin, nuclear membranes, specific cytoplasmic components, and microorganisms, facilitating detailed examination of cellular structures. Giemsa stain is widely utilized in cytological research and parasitological studies, allowing for enhanced visualization and analysis of cellular morphology and pathogen identification. -
Nucleic Acid/protein Dye
Wright's stain is a composite staining agent that primarily targets nucleic acids and proteins through the action of thiazine dyes, including methylene blue, and eosin. This pH-sensitive stain, optimal at pH 6.4-6.7, facilitates the differentiation of cytoplasmic and nuclear morphology by producing contrasting colors; thiazine dyes yield purple staining of nucleic acids, while eosin binds to cytoplasmic proteins to impart a red hue. Wright's stain effectively reveals fine structural details of blood and bone marrow cells, allowing for the rapid assessment of cell morphological abnormalities. -
Fluorescent Dye
Auramine O is a fluorescent dye primarily used for the detection of amyloid fibrils. It exhibits strong yellow fluorescence, making it valuable for visualizing cellular structures and assessing algal cell viability. Additionally, Auramine O is employed in staining acid-fast bacteria, thereby aiding in microbiological studies and cancer research involving lung malignancies. -
Antiseptic Dye
Methyl Blue is a triaminotriphenylmethane dye known for its antiseptic properties. It is commonly employed in histological and microbiological staining procedures, particularly within the polychrome staining technique. Additionally, Methyl Blue serves as a model compound for researching the effects of various catalysts on the photodegradation of dyes, facilitating studies in environmental chemistry and dye degradation pathways. -
Fluorescent Dye
5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride is a redox-sensitive fluorescent dye primarily used as a metabolic activity indicator in microorganisms. This compound emits red fluorescence with a maximum emission at 602 nm, enabling effective visualization and quantification of cellular metabolism. It serves as a valuable tool in microbiological studies, particularly for assessing viability and metabolic function in various microbial species. -
Dye
DMN-Tre is a fluorogenic dye that selectively targets the mycobacterial cell wall via the Ag85 enzymes. Its primary application lies in the diagnosis of tuberculosis, allowing for effective labeling of mycobacterial components. DMN-Tre serves as a valuable tool in research focused on infection and mycobacterial biology. -
Chromosome Dye
Jenner's Stain is a chromosome dye primarily used in microscopy for C-banding techniques. This reagent effectively stains blood smears, facilitating routine blood examinations and the identification of malaria parasites. Its application in cytogenetics allows for visualizing chromosomal structures, aiding in various research studies related to hematology and infectious diseases. -
Anthraquinone Dye
Reactive Blue 19 is an anthraquinone dye that primarily targets textile materials for coloration. This compound exhibits strong staining properties and is commonly used in both research and industrial applications for dyeing textiles and other substrates. Its vibrant hue and stability make it a valuable reagent in studies related to dye chemistry and material science. -
Cationic Dye
Pyronin B is an organic cationic dye primarily utilized for the selective staining of bacterial cells, mycobacteria, and ribonucleic acids. Its ability to penetrate cell membranes makes it a valuable tool for visualizing cellular components in microscopy applications. Additionally, Pyronin B serves as a small hydrophobic protein channel inhibitor, allowing researchers to investigate ion transport dynamics and membrane physiology in various biological systems. -
DNA Fluorescent Dye
Methyl Green Zinc Chloride is a fluorescent dye specifically targeting DNA. It is effective in staining cells and electrophoretic gels, allowing for the visualization of nucleic acids. This compound can be utilized for direct assessment of cell viability through microscopy and flow cytometry, exhibiting emission peaks at 633 nm and 677 nm. Its applications are important in molecular biology and biomedical research. -
Fluorescent Dye
sBADA is a sulfonated BODIPY-FL derivative that serves as a potent green fluorescent dye. Its primary mechanism involves the labeling of peptidoglycans within bacterial cell walls, facilitating in situ visualization. sBADA is particularly valuable in microbiological studies and applications focused on bacterial cell wall characterization. Emission is observed at 510 nm upon excitation at 490 nm, making it suitable for various fluorescence microscopy techniques. -
Phenazine Dye
Phenosafranine is a phenazine dye known for its high binding affinity to triple-stranded RNA, intercalating with both triple-stranded and double-stranded RNA. It also interacts with hemoglobin, making it a valuable tool in biological research. Phenosafranine is primarily utilized for plant cell staining and the detection of biomolecules such as hemoglobin, dopamine, and serotonin in various analytical applications. -
Diazo-Conjugate Red Dye
Sudan I, a diazo-conjugate red dye, primarily functions as a colorant in various applications, including oils, solvents, and polishes. This compound is known to inhibit the growth of specific bacterial strains, such as Clostridium perfringens and Lactobacillus rhamnosus. Its antimicrobial properties make it a valuable tool in microbiological research and product formulation studies. -
Fluorescent Probe
BIN-3 is a near-infrared fluorescent probe that targets drug-resistant bacterial infections by selectively imaging β-lactamase enzymes. Demonstrating excellent biocompatibility and a lack of cytotoxicity and hemolytic effects, BIN-3 is suitable for in vivo imaging applications in live mice. Its high sensitivity and selectivity make it an invaluable tool for researchers studying antibiotic resistance and bacterial pathogenesis. -
Green Fluorescent D-amino Acid
OGDA is a green fluorescent D-amino acid that serves as a valuable tool for the selective labeling of peptidoglycan in both Gram-positive and Gram-negative bacteria. Its fluorescent properties facilitate the visualization of bacterial cell walls, enhancing studies on bacterial morphology and structure. This compound is particularly useful in microbiological research and applications involving bacterial imaging and tracking. -
Fluorescent Indicator
1,3-Di-(2-pyrenyl)propane functions as a fluorescent indicator that is particularly useful for monitoring the fluidity of bacterial membrane lipids through intramolecular excimerization. This compound exhibits temperature-dependent fluorescence lifetime distributions, making it valuable for studying membrane dynamics and cellular responses to thermal variations. Its unique photophysical properties facilitate research in membrane biophysics and related biological applications. -
Fluorescent Dye
Cy3-NO2-Tre is a nitroreductase-responsive cyanine-based fluorescent dye designed for the specific labeling of Mycobacterium tuberculosis (Mtb). Upon activation by the conserved nitroreductase Rv3368c found in the Mycobacteriaceae family, it exhibits fluorescence, facilitating the imaging of mycobacteria within infected host cells. This fluorescent probe is valuable for tracking infection dynamics and visualizing the endocytosis of Mycobacterium smegmatis by macrophages, with excitation/emission wavelengths of 540-550/575-625 nm. -
β-amyloid Dye
Thioflavin T is a cationic benzothiazole dye that selectively binds to β-amyloid fibrils, resulting in a significant increase in fluorescence. The dye exhibits an excitation maximum at approximately 385 nm when unbound and around 450 nm when bound to amyloid, with emission maxima of approximately 445 nm and 485 nm, respectively. It is widely used in research to detect and study amyloid deposition in tissues, contributing to the understanding of neurodegenerative diseases such as Alzheimer's. -
G-quadruplex DNA Fluorescent Binder
N-Methylmesoporphyrin IX (NMM) is a potent fluorescent binder that targets G-quadruplex DNA, making it an effective probe for studying Aβ fibrillation. It serves as both an in situ inhibitor and an ex situ monitor of Aβ amyloidogenesis in vitro and within cellular contexts. NMM exhibits high sensitivity to G-quadruplex structures while showing negligible response to duplexes, triplexes, and single-stranded DNA. Additionally, it remains nonfluorescent in monomeric Aβ environments, producing strong fluorescence upon interaction with Aβ aggregates. -
Dye Molecule
Eosin Y (Acid Red 87 free base) is a soluble acid dye known for its role as a photoredox catalyst. This dye exhibits strong absorbance in the visible light spectrum, facilitating various organic synthesis reactions. Eosin Y is commonly utilized in photochemical applications, enabling the generation of reactive intermediates for diverse chemical transformations. -
Azo Dye
Congo Red is an azo dye that specifically binds to amyloid proteins. Its primary application is as a histological stain for the detection of amyloid deposits in tissue sections, facilitating the diagnosis of amyloidosis and related diseases. Additionally, Congo Red is utilized in various research studies to investigate protein aggregation and misfolding, making it a valuable reagent in both clinical and experimental settings. -
Dye/P2×7R Antagonist
Brilliant Blue G-250 is a dye that functions as a P2×7 receptor (P2×7R) antagonist. It exhibits selective inhibition of P2×7R, leading to the inactivation of the NLRP3 inflammasome, which is crucial in inflammatory processes. This compound is widely utilized for protein visualization in SDS-PAGE, providing a straightforward staining method alongside high quantitation capabilities in the Bradford protein assay, where protein concentrations are assessed by measuring absorbance at 595 nm. -
Fluorescent Probe
NTPAN-MI is a fluorescent probe that operates through selective activation upon labeling unfolded proteins with exposed thiols. Functioning as a sensitive indicator of protein homeostasis, NTPAN-MI emits fluorescence at an excitation wavelength of 405 nm. This probe is invaluable for researchers investigating protein folding, stability, and the cellular stress response in various biological systems. -
Anionic Dye
Brilliant Blue R250 is an anionic dye primarily used for protein detection in SDS-PAGE gels. This dye effectively binds to proteins, providing clear visualization and enabling quantification of protein samples. It is widely utilized in biochemical research for analyzing protein purity and assessing protein molecular weight. -
Calcium Deposits Dye
Alizarin Red S sodium is an anthraquinone-derived dye that specifically targets calcium deposits. This reagent forms coordination bonds with calcium ions, resulting in an orange-red fluorescence that can be detected under excitation at 500 nm and emission at 570 nm. Alizarin Red S sodium is widely used in research applications for screening calcium compounds in synovial fluid, detecting osteoblast differentiation, and visualizing bone structures in murine models.
